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UCSF Study Tests Whether Sleep Loss Affects Covid Vaccine

written by / April 22, 2021
UCSF Study Tests Whether Sleep Loss Affects Covid Vaccine

Amid the struggle for individual and herd immunity against COVID-19, people wonder about the effectiveness of different vaccines. Yet, they tend to forget one key aspect of the whole immunization process — their immune reaction

Indeed, all available COVID-19 vaccines are remarkably effective against the virus in the short run, but how long the protection lasts is still unknown. Each individual that has been tested for antibodies shows different results. 

The factors that can modify the immune response to the coronavirus vaccine are in the focus of a new UCSF study called the Building Optimal Antibodies Study (or BOOST). 

Similar studies reveal that sleep, stress, age, and obesity can influence vaccine efficacy (flu shot, Hepatitis B) and viral infection risk (common cold).

A study of the UC of San Francisco showed that lack of sleep inhibits our immunity and makes us four times more susceptible to catching a cold, regardless of age, weight, and race. 

What’s more, researchers found out that anxiety and psychological strain promote the fading of some vaccines’ efficacy.

BOOST will check whether this is also true for the vaccines against COVID-19. 

Given how complicated and slow the vaccination process is, the goal is to get the most out of it — in other words, a longer-lasting immunity.

The desired response is the massive production of T cells (killer cells) and B cells that produce specific antibodies against COVID-19

The study will evaluate both in participant’s blood one and six months after vaccination. The subject’s emotional state, anxiety level, sleep, and health parameters will be assessed through a short questionnaire. 

If it’s true that sleep and stress affect vaccine outcomes, coronasomnia sufferers are in for a ride. Still, everyone can join the fight against COVID-19 by choosing a good mattress, sleep aid, or simply relaxing more.

Marija Kovachevska is a content writer at, Biochemist and Activist. After obtaining her BSc in Biochemistry and Physiology she changed her microscope for content research tools and continued researching in the fields of Medicine, Biology, and Communication. Her insatiable curiosity flare drove her to become a “content scientist writer” as she likes to say. Reality fascinates her and facts and statistics are a must-have feature in her articles. Fluent in English and French, she is a volunteer and communication associate for several non-profit organizations. French culture and handcrafting are her passion, but in her free time, she indulges in long walks and traveling, or as she likes to say “experiencing the inexperienced.”

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